导师简介赵友兴，男，研究员，硕导，中国热带农业科学院热带生物技术研究所

邮 箱：zhaoyouxing@itbb.org.cn

通讯地址：海南省海口市龙华区学院路4号

邮政编码：571101研究领域：药用植物与菌物中活性天然产物发现与评价招生专业

硕士研究生：农艺与种业（095131）资源利用与植物保护（095132）教育背景

2001-03—2004-07 中国科学院昆明植物研究所 博士

1998-09—2001-01 南京农业大学 硕士

1994-09—1998-07 南京农业大学 学士

学历：博士研究生

学位：博士工作简历

2013-01—至今 中国热带农业科学院热带生物技术研究所 研究员

2010-11—2012-12 中国热带农业科学院热带生物技术研究所 副研究员

2007-01—2010-10 中国科学院昆明植物研究所工作 副研究员

2004-08—2006-12 中国科学院昆明植物研究所工作 助理研究员目前承担的课题

1) 海南省自然科学基金创新团队项目，2019CXTD411，海洋真菌新颖次生代谢产物的发现及其活性评估，2019/03-2021/12，45万元，主持；

2) 农业农村部农业农村资源等监测统计专项，NFZX2018,南海海洋生物资源的调查与评估，2018/01-2020/12, 290万,主持；

3) 中国热带农业科学院基本科研业务费，17CXTD-15，南药产业技术创新团队，2017/01-2021/12，50万，主持。

发表论文

1.Fan-Dong Kong, Xiao-Long Huang, Qing-Yun Ma, Qing-Yi Xie, Pei Wang, Peng-Wei Chen, Li-Man Zhou, Jing-Zhe Yuan, Hao-Fu Dai, Du-Qiang Luo*, You-Xing Zhao*. Helvolic Acid Derivatives with Antibacterial Activities against Streptococcus agalactiae from the Marine-Derived Fungus Aspergillus fumigatus HNMF0047. Journal of Natural Products, 2018, 81: 1869-1876. (SCI)

2.Chang-Liang An, Fan-Dong Kong, Qing-Yun Ma, Qing-Yi Xie, Jing-Zhe Yuan, Li-Man Zhou, Hao-Fu Dai, Zhi-Fang Yu*, and You-Xing Zhao*. Chemical Constituents of the Marine-Derived Fungus Aspergillus sp. SCS-KFD66. Marine Drugs, 2018, 16: 468. (SCI)

3.Qing-yi Xie, Xiao-dong Bao, Qing-yu Ma, Fan-dong Kong, Man-li Zhou, Bing Yan, You-xing Zhao*. Verrucosispora rhizosphaerae sp. nov., isolated from mangrove rhizosphere soil. Antonie van Leeuwenhoek. 2018, 111: 125-133. (SCI)

4.Shuang Yang, Qing-Yun Ma, Fan-Dong Kong, Qing-Yi Xie, Sheng-Zhuo Huang, Li-Man Zhou, Hao-Fu Dai, Zhi-Fang Yu*, You-Xing Zhao*. Two new compounds from the fruiting bodies of Ganoderma philippii. Journal of Asian Natural Products Research, 2018, 20 (3): 249-254. (SCI)

5.Sheng Zhuo Huang, Qing Yun Ma, Qi Wang, Hao Fu Dai, Yu Qing Liu, Jun Zhou*, You Xing Zhao*. Daphnauranins C–E, three new antifeedants from Daphne aurantiaca roots. Molecules, 2018, 23 (10), 2429. (SCI)

6.Qing-Yun Ma, Shuang Yang, Sheng-Zhuo Huang, Fan-Dong Kong, Qing-Yi Xie, Hao-Fu Dai, Zhi-Fang Yu*, You-Xing Zhao*. Ergostane steroids from Coprinus setulosus. Chemistry of Natural Compounds, 2018,?54 (4): 710-713. (SCI)

7.Zhong Wang, Peng Fan, Tong-Dan Xue, Lin-Lin Meng, Wen-Bin Gao, Jun Zhang, You-xing Zhao*, Du-Qiang Luo*. Two New Isocoumarin Derivatives from an Endophytic Fungi Pestalotiopsis coffeae Isolated from a Mangrove Fishtail Palm. Natural Product Communications, 2018, 13 (1): 57-59. (SCI)

8.Qing-Yun Ma, Yong-Lei Chen, Sheng-Zhuo Huang, Fan-Dong Kong, Hao-Fu Dai, Yan Hua*, You-Xing Zhao*. Two new lignans from Wikstroemia dolichantha Diels. Chemistry of Natural Compounds, 2018,?54 (1): 22-25. (SCI)

9.孔凡栋，张宇，马青云，谢晴宜，周丽曼，邓世明*，赵友兴*.海洋真菌Penicillium sp. SCS-KFD16次级代谢产物研究. 中草药，2018，49（21）：5029-5033.

10.黄圣卓，刘玉清，马青云，孔凡栋，王琪，戴好富，周俊*，赵友兴*.橙黄瑞香茎中酚性成分研究.中药材，2018，41（3）：590-594.

11.李冉，马青云，孔凡栋，谢晴宜，丁琼*，赵友兴*.木蹄层孔菌子实体的化学成分分析.热带生物学报，2018，9（4）：445-451.

12.Fan Dong Kong, Li Man Zhou, Qing Yun Ma, Sheng Zhuo Huang, Pei Wang, Hao Fu Dai, You-Xing Zhao*. Metabolites with Gram-negative bacteria quorum sensinginhibitory activity from the marine animal endogenic fungus Penicillium sp. SCS-KFD08. Archives of Pharmacal Research, 2017, 40 (1): 25-31. (SCI)

13.Fan-Dong Kong, Qing-Yun Ma, Sheng-Zhuo Huang, Pei Wang, Jun-Feng Wang, Li-Man Zhou, Jing-Zhe Yuan, Hao-Fu Dai*, You-Xing Zhao*. Chrodrimanins K?N and related meroterpenoids from the fungus Penicillium sp. SCS-KFD09 isolated from a marine worm, Sipunculus nudus. Journal of Natural Products, 2017, 80: 1039-1047. (SCI)

14.Sheng-Zhuo Huang, Qing-Yun Ma, Fan-Dong Kong, Zhi-Kai Guo, Qi Wang, Hao-Fu Dai, Yu-Qing Liu, Jun Zhou,* and You-Xing Zhao*. Daphnauranins A and B, two new antifeedantsIsolated from Daphne aurantiaca roots. Fitoterapia, 2017, 122: 11-15. (SCI)

15.Fan-Dong Kong, Ren-Shuai Zhang, Qing-Yun Ma, Qing-Yi Xie, Pei Wang, Peng-Wei Chen, Li-Man Zhou, Hao-Fu Dai, Du-Qiang Luo* and You-Xing Zhao*. Chrodrimanins O-S from the Fungus Penicillium sp. SCS-KFD09 Isolated from a Marine Worm, Sipunculusnudus. Fitoterapia, 2017, 122 : 1-6. (SCI)

16.Sheng-Zhuo Huang, Qing-Yun Ma, Fan-Dong Kong, Zhi-Kai Guo, Cai-Hong Cai, Li-Li Hu, Li-Man Zhou, Qi Wang, Hao-Fu Dai, Wen-Li Mei, You Xing Zhao*. Lanostane-type triterpenoids from the fruiting body of Ganoderma calidophilum. Phytochemistry, 2017, 143: 104-110. (SCI)

17.Ning-Ning Yang, Qing-Yun Ma, Sheng-Zhuo Huang, Fan-Dong Kong, Hao-Fu Dai, Zhi-Fang Yu*, You-Xing Zhao*. Chemical study of the fungus Psilocybe merdaria. Journal of Asian Natural Products Research, 2017, 19 (4): 333-338. (SCI)

18.Ning Ning Yang, Fan Dong Kong, Qing Yun Ma, Sheng Zhuo Huang, Du Qiang Luo, Li Man Zhou, Hao Fu Dai, Zhi Fang Yu*, You Xing Zhao*. Drimane-type sesquiterpenoids from cultures of the fungus Xylaria polymorpha. Phytochemistry Letters, 2017, 20: 13-16. (SCI)

19.Fandong Kong, Qingyun Ma, Shengzhuo Huang, Shuang Yang, Linran Fu, Liman Zhou, Haofu Dai, Zhifang Yu2*, Youxing Zhao*. Tetracyclic indole alkaloids with anti-nematode activity from Uncaria rhynchophylla. Natural Product Research, 2017, 31 (12): 1403-1408. (SCI)

20.Ning Ning Lan, Qing Yun Ma, Fan Dong Kong, Ning Ning Yang, Qing Yi Xie, Sheng Zhuo Huang, Li Man Zhou, You Gen Wu*, You Xing Zhao*.Two new nortriterpenoids from the fruiting bodies of Ganoderma daqingshanense. Phytochemistry Letters, 2017, 22: 210-213. (SCI)

21.杨宁宁，孔凡栋，马青云，黄圣卓，罗都强，周丽曼，戴好富，郁志芳*，赵友兴*.多形炭角菌Xylaria polymorpha菌丝发酵的次级代谢产物研究. 有机化学，2017，37:1033-1039.(SCI)

22.Jun Zhang, Lin-Lin Meng, Jing-Jing Wei, Peng Fan, Sha-Sha Liu, Wei-Yu Yuan, You-Xing Zhao*, Du-Qiang Luo*. PTP1B Inhibitors from the Entomogenous Fungi Isaria fumosorosea. Molecules, 2017, 22, 2058. (SCI)

23.兰宁宁，马青云，黄圣卓，孔凡栋，杨宁宁，戴好富，吴友根*，赵友兴*. 大青山灵芝的化学成分研究. 中草药，2017，48（3）：437-442.

24.张宇，孔凡栋，马青云，黄圣卓，周丽曼，戴好富，邓世明*，赵友兴*.海洋真菌Aspergillus sp. SCS-KFD03化学成分研究.中国海洋药物，2017，36（2）：15-21.

25.王林，孔凡栋，马青云，黄圣卓，周丽曼，谢晴宜，丁琼*，赵友兴*.考夫曼网柄牛肝菌子实体的化学成分. 热带生物学报，2017，8（4）：466-473.

26.李冉，马青云，孔凡栋，谢晴宜，丁琼*，赵友兴*.木层孔菌属真菌的化学成分及其生物活性的研究进展.热带生物学报，2017，8（4）：488-494.

27.孔凡栋，周丽曼，马青云，黄圣卓，赵友兴*.革兰氏阴性细菌LuxR/I型群体感应抑制剂研究进展. 现代生物医学进展，2017，17（30）：5984-5988.

28.王林，马青云，黄圣卓，孔凡栋，丁琼，赵友兴*.牛肝菌化学成分及其生物活性的研究进展.热带生物学报，2017，8（1）：127-132.

29.张宇，孔凡栋，马青云，谢晴宜，黄圣卓，周丽曼，戴好富，邓世明*，赵友兴*.海洋真菌Aspergillus sp. SCS-KFD03化学成分分析.热带生物学报，2017，8（3）：42-48.

30.孔凡栋，周丽曼，马青云，黄圣卓，赵友兴*.革兰阳性细菌AIP型群体感应抑制剂研究进展. 热带生物学报，2017，8（2）：236-240.

31.谌永蕾，马青云，黄圣卓，孔凡栋，谢晴宜，华燕，赵友兴*.构皮荛花的化学成分研究. 时珍国医国药.2017,28（10）：2339-2343.

32.Sheng-Zhuo Huang, Fan-Dong Kong, Qing-Yun Ma, Zhi-Kai Guo, Li-Man Zhou, Qi Wang, Hao-Fu Dai,* You-Xing Zhao*. Nematicidal Stemona Alkaloids from Stemona parviflora. Journal of Natural Products, 2016, 79: 2599-2605. (SCI)

33.Peng-Cheng Wang, Xin-Hui Ran, Huai-Rong Luo, Qing-Yun Ma, Jun Zhou, Jiang-Miao Hu,* and You-Xing Zhao*. Volvalerine A, an unprecedented N-containing sesquiterpenoid dimer derivate from Valeriana officinalis var. latifolia. Fitoterapia, 2016, 109 (3): 174-178. (SCI)

34.Qing-Yun Ma, Sheng-Zhuo Huang, Li-Li Hu, Zhi-Kai Guo, Hao-Fu Dai, You-Xing Zhao*. Two new tirucallane triterpenoids from the fruiting bodies of Ganoderma tropicum. Chemistry of Natural Compounds, 2016,?52 (4): 656-659. (SCI)

35.Sheng Zhuo Huang, Bao Hui Cheng, Qing Yun Ma, Qi Wang, Fan Dong Kong, Hao Fu Dai, Shu Qi Qiu, Peng Yuan Zheng, Zhi Qiang Liu,* You-Xing Zhao*. Anti-allergic Prenylated Hydroquinonesand Alkaloids from the Fruiting Body of Ganoderma calidophilum. RSC Advances, 2016, 6: 21139-21147. (SCI).

36.Fan Dong Kong, Li Man Zhou, Qing Yun Ma, Sheng Zhuo Huang, Pei Wang, Hao-Fu Dai, You-Xing Zhao*. Penicillars A–E from the marine animal endogenic fungus Penicillium sp. SCS-KFD08. Phytochemistry Letters, 2016, 17: 59-63. (SCI)

37.Qiao Wang, Yu-Guang Wang, Qing-Yun Ma, Sheng-Zhuo Huang, Fan-Dong Kong, Li-Man Zhou, Hao-Fu Dai, You-Xing Zhao*. Chemical constituents from the fruiting bodies of Amauroderma subresinosum. Journal of Asian Natural Products Research, 2016, 18 (11): 1030-1035. (SCI)

38.Qing-Yun Ma, Yi-Chun Chen, Sheng-Zhuo Huang, Fan-Dong Kong, Li-Man Zhou, Hao-Fu Dai, Yan Hua *, You-Xing Zhao*. Chemical constituents from the stems of Daphne holosericea (Diels) Hamaya. Chemistry & Biodiversity, 2016, 13: 1469-1474. (SCI)

39.谌永蕾，马青云，黄圣卓，戴好富，华燕*，赵友兴*. 皱盖假芝子实体的化学成分研究. 中草药，2016，47（6）：881-885.

40.黄圣卓，王琪，刘玉清，周俊，戴好富，马青云，孔凡栋，赵友兴*. 橙黄瑞香中苯丙素类成分研究. 中草药，2016，47（22）：3970-3974.

41.兰宁宁，马青云，黄圣卓，孔凡栋，戴好富，吴友根，赵友兴*.灵芝安全性研究进展.热带生物学报，2016，7（1）：128-130.

42.Sheng-Zhuo Huang, Xuan Zhang, Qing-Yun Ma, Yong-Tang Zheng, Hao-Fu Dai, Qi Wang, Jun Zhou * and You-Xing Zhao*. Anti-HIV terpenoids from Daphne aurantiaca Diels. stems. RSC Advances, 2015, 5 (98): 80254-80263. (SCI)

43.Ningning Yang, Qingyun Ma, Shengzhuo Huang, Haofu Dai, Zhikai Guo, Xuehua Lu, Yuguang Wang, Zhifang Yu*, Youxing Zhao*. Chemical constituents from cultures of the fungus Marasmiellus ramealis (Bull.) Singer. Journal of the Brazilian Chemical Society, 2015, 26 (1): 9-13. (SCI)

44.Shuang-Shuang Zhang, Qing-Yun Ma, Sheng-Zhuo Huang, Hao-Fu Dai, Zhi-Kai Guo, Zhi-Fang Yu*, You-Xing Zhao*. Lanostanoids with acetylcholinesterase inhibitory activity from the mushroom Haddowia longipes. Phytochemistry, 2015, 110 (2): 133-139. (SCI)

45.Qingyun Ma,?Qinli Wan,?Shengzhuo Huang,?Haofu Dai,?Yingrui Wu,?Jun Zhou,?Huairong Luo*, Youxing Zhao*. Phenolic constituents with inhibitory activities on acetylcholinesterase from the rhizomes of?Gastrodia elata. Chemistry of Natural Compounds, 2015,?51 (1): 158-160. (SCI)

46.Shuang-Shuang Zhang, Yu-Guang Wang, Qing-Yun Ma, Sheng-Zhuo Huang, Li-Li Hu, Hao-Fu Dai, Zhi-Fang Yu*, You-Xing Zhao*. Three new lanostanoids from the mushroom Ganoderma tropicum. Molecules, 2015, 20, 3281-3289. (SCI)

47.Ning-Ning Yang, Sheng-Zhuo Huang, Qing-Yun Ma, Hao-Fu Dai, Zhi-Kai Guo, Zhi-Fang Yu*, You-Xing Zhao*. A new pyrrole alkaloid from Leccinum extremiorientale. Chemistry of Natural Compounds, 2015,?51 (4): 730-732. (SCI)

48.Huang Sheng Zhuo, Huang Hui Ni, Ma Qing Yun, Mo Ming He*, Zhu Ming Liang, Dai Hao Fu, Ji Yan Ping, Wang Qing Hai, Zhao You Xing*. The Phytochemicals with antagonistic activities toward pathogens of a disease complex caused by Meloidogyne incognita and Ralstonia solanacearum. Journal of Pure and Applied Microbiology. 2015, 9 (1): 209-213.

49.傅淋然，马青云，黄圣卓，郁志芳*，赵友兴*.灰毛浆果楝茎的化学成分.中草药，2015,46（5）：633-638.

50.杨丹, 马青云, 程忠泉, 黄圣卓, 莫明和, 赵友兴*.茯苓皮中三萜成分的分离鉴定及其生物防治活性.贵州农业科学，2015,43（4）：100-103.

51.Sheng-Zhuo Huang, Xiao-Nian Li, Qing-Yun Ma, Hao-Fu Dai, Liang-Chun Li, Xiang-Hai Cai, Yu-Qing Liu, Jun Zhou*, You-Xing Zhao*. Daphnauranols A-C, new antifeedant sesquiterpenoids with a 5/6/7 ring system from Daphne aurantiaca. Tetrahedron Letters, 2014, 55 (27): 3693-3696. (SCI)

52.Sheng-Zhuo Huang, Huai-Rong Luo, Qing-Yun Ma, Hua Peng, Hao-Fu Dai, Jun Zhou*, You-Xing Zhao*. Chemical constituents from the stems of Excoecaria acertiflia. Chemistry & Biodiversity, 2014, 11 (9): 1406-1416. (SCI)

53.Qing-Yun Ma, Yi-Chun Chen, Sheng-Zhuo Huang, Zhi-Kai Guo, Hao-Fu Dai, Yan Hua* and You-Xing Zhao*. Two new guaiane sesquiterpenoids from Daphne holosericea (Diels) Hamaya. Molecules, 2014, 19 (9): 14266-14272. (SCI)

54.Lin-Ran Fu, Qing-Yun Ma, Sheng-Zhuo Huang, Hao-Fu Dai, Zhi-Kai Guo, Zhi-Fang Yu*, You-Xing Zhao*. Terpenoids and their anti-feedant activity from Cipadessa cinerascens. Journal of Asian Natural Products Research. 2014, 16 (11): 1054-1059. (SCI)

55.Ningning Yang, Qingyun Ma, Shengzhuo Huang, Haofu Dai, Zhikai Guo, Zhifang Yu* Youxing Zhao*. Two rostane derivatives from the cultures of fungus Marasmiellus ramealis (Bull.) Singer. Bulletin of the Korean Chemical Society, 2014, 35 (11): 3224-3226. (SCI)

56.Li-Li Hu, Qing-Yun Ma, Sheng-Zhuo Huang, Zhi-Kai Guo, Hai-Xia Ma, Jian-Chun Guo, Hao-Fu Dai*, You-Xing Zhao*. A new nortriterpenoids from the fruiting bodies of Ganoderma tropicum Phytochemistry Letters, 2014, 7 (1): 11-13. (SCI)

57.Sheng-Zhuo Huang, Xuan Zhang, Qing-Yun Ma, Hua Peng, Wei-Wei Fang, Yong-Tang Zheng, Jiang-Miao Hu, Hao-Fu Dai , Jun Zhou*, You-Xing Zhao*. Anti-HIV-1 tigliane diterpenoids from Excoecaria acertiflia Didr. Fitoterapia, 2014, 95 (4): 34-41. (SCI)

58.黄圣卓，马青云，彭华，牛洋，刘玉清，周俊*，赵友兴*.云南土沉香中的香豆素类成分研究. 中草药，2014，45(3): 318-322.

59.杨宁宁，黄圣卓，马青云，戴好富，郁志芳*，赵友兴*. 远东疣柄牛肝菌化学成分分析. 食品科学，2014,35（6）：78-82.

60.马青云，黄圣卓，戴好富，梅文莉，莫明和*，赵友兴*. 红毛丹果壳中齐墩果烷型三萜苷类成分的生防活性. 热带生物学报，2014，5（4）：334-338.

61.罗应，马青云，黄圣卓，郭志凯，戴好富，赵友兴*. 海南灵芝化学成分研究. 热带亚热带植物学报，2014，22（2）：190-194.

62.马青云，王桥，吴兴亮，黄圣卓，赵友兴*. 松杉灵芝化学成分及药理活性的研究进展. 贵州科学，2014，32（3）：21-24.

63.陈义纯，马青云，黄圣卓，郭志凯，赵友兴*，华燕*. 丝毛瑞香化学成分分析. 西南林业大学学报，2014,34（1）：97-101.

64.杨爽，马青云，黄圣卓，戴好富，郭志凯，郁志芳*，赵友兴*.橡胶灵芝化学成分研究.中国中药杂志，2014,39（6）：1034-1039.出版著作

1) 中国药用真菌, 主编, 2013, 科学出版社获授权专利

1) 赵友兴，孔凡栋，周丽曼，马青云，黄圣卓，戴好富. 一种改善学习记忆的中药组合物及其制备方法.（专利号：ZL 201510753667.3）

2) 赵友兴，孔凡栋，周丽曼，马青云，黄圣卓，戴好富. 一种具有降血脂功效的中药组合物及其制备方法与用途.（专利号: ZL 201510743094.6）

3) 马青云，赵友兴，黄圣卓，戴好富，王辉. 一种减肥降脂的中药组合物、制剂及食品.（专利号：ZL 2012 1 0259317.8）

4) 赵友兴，马青云，黄圣卓，戴好富，罗应，王辉. 一种治疗抑郁症的中药组合物及其制备方法和应用.（专利号：ZL 2012 1 0288312.8）

5) 赵友兴，马青云，黄圣卓，戴好富，王辉. 一种改善睡眠的中药组合物及其制备方法和应用.（专利号：ZL 2012 1 0288313.2）成果与奖励

1）中国产学研合作创新成果优秀奖，2016（4）

2）海南省科学技术进步一等奖，2015（3）

3）海南省科学技术进步二等奖，2013（5）

4）海口市科学技术进步奖一等奖，2013（5）获得省级以上人才称号与学术兼职

1) 海南省高层次人才